Over-the-counter (OTC) products are medicines you can buy without a doctor’s prescription.

Antacids reduce the effect of (neutralize) the acid in your stomach. They can provide fast, short-term relief. Many OTC medicines combine different antacids.

H2 blockers reduce the amount of acid your stomach makes. While they don’t relieve symptoms right away, H2 blockers relieve symptoms for a longer period of time than antacids. They usually start to work within an hour. Examples of H2 blockers available over the counter are ranitidine (brand name: Zantac) or famotidine (brand name: Pepcid).

Proton pump inhibitors greatly reduce your body’s production of acid. They work well for that isn’t resolved by antacids or H2 blockers. It may take a little longer for a proton pump inhibitor to help your symptoms than an H2 blocker, but relief will last longer. These medicines are most helpful for people who have heartburn often — more than two days a week. Omeprazole (brand name: Prilosec) is an example of a proton pump inhibitor.


Alka Seltzer Extra Strength Antacid And Pain Relief Tablets - 12 Ea

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CODE: 016500044024

Marketplace Price: $4.20

Price: $3.78

You save: $0.42 (10%)
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  • For the relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains; upset stomach with headache from over-indulgence in food and drink; headache, body aches, and pain alone.

Active Ingredients:

  • (in each tablet): Aspirin 500 mg (Analgesic), Citric Acid 1000 mg (Antactid), Sodium Bicarbonate (heat-treated) 1985mg (Antacid).

Inactive Ingredients:

  • Flavors.


  • Fully dissolve tablets in 4 ounces of water before taking.
  • Adults and children 12 years and over: 2 tablets every 6 hours, or as directed by a doctor. Do not exceed 7 tablets in 24 hours.
  • Adults 60 years and over: 2 tablets every 6 hours, or as directed by a doctor. Do not exceed 4 tablets in 24 hours.


  • Reye's Syndrome:  Children and teenagers should not use this medicine for chicken pox or flu symptoms before a doctor is consulted about Reye Syndrome, a rare but serious illness reported to be associated with aspirin.
Alka Seltzer Extra Strength Antacid And Pain Relief Tablets.